Single is sometimes best

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Promoting workplace stair climbing: sometimes, not interfering is the best

BACKGROUND Stair climbing is a vigorous activity and can lead to several health benefits. Studies seeking to increase stair climbing in various public locations have shown positive effects, while results from similar studies conducted in the workplace are inconclusive. This study examined stair climbing in the workplace, and monitored effects from a single- and a combined intervention. Interven...

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Sometimes, more is better.

(See the article by El Sahly et al, on pages 703–12.) Influenza causes significant morbidity and mortality with an estimated 36 000 attributable deaths in the United States annually [1]. Human immunodefi-ciency virus (HIV) infection, specifically , advanced disease (CD4 count ,200 cells/lL), has been associated with excess morbidity and mortality [2]. With the use of combination antiretroviral ...

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Sometimes Average is Best: The Importance of Averaging for Prediction using MCMC Inference in Topic Modeling

Markov chain Monte Carlo (MCMC) approximates the posterior distribution of latent variable models by generating many samples and averaging over them. In practice, however, it is often more convenient to cut corners, using only a single sample or following a suboptimal averaging strategy. We systematically study different strategies for averaging MCMC samples and show empirically that averaging ...

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Peritonitis and zoonosis: your best friend sometimes isn't!

Approximately 60% of all households in the United States have a pet, with about 74.8 million owning a dog and 25% having two dogs. There are approximately 88.3 million cat owners in the USA, with 56% of them having more than one cat (1). While the bond with animals for companionship goes back 10 000 – 15000 years, domestic pets are also capable of transmitting diseases and causing injury. Zoono...

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ژورنال

عنوان ژورنال: Nature Reviews Molecular Cell Biology

سال: 2006

ISSN: 1471-0072,1471-0080

DOI: 10.1038/nrm1926